Lyon is pretty great. Depending on the vibe you’re going for, Marseille is also pretty awesome. I’d avoid it in the middle of the summer, but shoulder season down south is amazing. The weather is great, the people are friendly (if you avoid the worst parts of town, like anywhere) and the food is a nice mix of traditional French and Mediterranean cuisine. And make sure to get a flight of Ricard.

As an Anglophone who lives in France, I agree. Although where I live (east / south-east) English is not very widely spoken, even in bigger cities, but the people are generally very friendly.