A lot of stuff does run.
- Steam (proton)
- Heroic Launcher (Epic Games, Gog, Prime gaming)
- Wine for additional Windows based Programs
The only Thing that I do Miss, is Anti-Cheat Software for some games. Thats the only reason to keel dualboot, to Launch that Games on Windows. Besides that - screw Windows.
You can Download an .AppImage from their Website directly. Just make it executable and there you Go. Decent UI and pretty straight forward