Yes quite a few as other commenters have indicated. Another good one is !boinc@sopuli.xyz. BOINC is an open source platform for volunteer computing that also has hundreds of scientific papers and citations under its belt. There are BOINC projects for medical research, space research, math, you name it, there’s probably a BOINC project for it. Anybody can start a BOINC project and you choose which projects you contribute CPU/GPU time to. You can pick more than one at a time. You may recognize some of the people hosting BOINC projects: Large Hardon Collider, Max Planck Institute, University of Washington Institute for Protein Design, etc
Not a distro but Qubes. Incredible security and privacy out of the box. Not for everyone but absolutely one of the most interesting developments in the OS world in the past decade or two.