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Cake day: July 1st, 2023

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  • protist@mander.xyztoAsklemmy@lemmy.mlHave you ever smoked crack? What was it like?
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    1 month ago

    This is pretty easy to search, but also intuitive when you consider crack is most often smoked vs cocaine being absorbed through your nasal mucosa. Here are a few highlights from this comprehensive review, which also covers the very real socioeconomic differences in use patterns:

    By virtue of its hydrophilicity, cocaine hydrochloride is generally consumed by ‘snorting.’ ‘Crack’ cocaine is generally the only form of cocaine that is smoked—this is due to the fact that cocaine hydrochloride has an elevated boiling point and does not vaporise at the temperatures of combustion.

    ®outes that involve the respiratory system…allow for the stimulant to reach the brain circulation in around 6 to 8 s; the inhalation route presents higher peak plasma concentrations that are reached faster when compared to intranasal administration. It should be noted that, for the intranasal route, the vasoconstrictive properties of cocaine slow down the drug’s own absorption, causing a 60-min delay of peak plasmatic concentrations. In terms of bioavailability, the inhalation route has the greatest bioavailability, which surpasses 90%, while the intranasal route has roughly 80%.

    The abuse and dependence of cocaine is strongly related to the drug’s capacity to induce the release of dopamine within the mesocorticolimbic circuit (also known as the reward system). As the user continues to consume cocaine, desensitization occurs and so larger doses are necessary to induce stimuli of the same magnitude as before, as well as to minimize withdrawal symptoms.

    Another difference of inhalation vs intranasal:

    Smoking ‘crack’ leads to the formation of another biomarker of exposure, AEME, which is the main product of cocaine’s thermal degradation. In vitro and in vivo studies show that AEME appears to have effects on the cardiovascular system, by acting as a muscarinic agonist. Furthermore, neurotoxic effects were also reported for this metabolite.


  • protist@mander.xyztoAsklemmy@lemmy.mlHave you ever smoked crack? What was it like?
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    1 month ago

    Let’s be real though, crack is significantly more addictive than regular cocaine. The high is higher, it lights up all the dopamine receptors in your brain. The high is much shorter, and the crash is much harder, which pushes users to use more to avoid intolerable withdrawal symptoms. Cocaine is “mellower” in pretty much every way. All the bad parts of cocaine use are only magnified in crack use. All this is completely independent of fucked up drug policy





  • Highly dependent on the job. I’m a SW who hires SWs. New grad LMSWs can start at $60K in hospitals or some government jobs, or $40K in schools or some nonprofits. 5-10 years of experience and a clinical license and you’ll easily pull $75-80K, or $90K+ in management.

    Then there’s private psychotherapy practice, which I know some people who charge $200/hour out of pocket and are scheduled out for months.

    All this to say getting a master’s in social work was one of the best decisions I’ve ever made, and I have no regrets financially, but there are some people who do end up in very low paid jobs