Yes, Docker apps are more appropriate for servers and most apps are “made” to run 24/7 to serv the home or workplace.
They are very much worth the “work to setup” as they can be transfered/replicated to any system.
Flatpak and the alike are for running apps on a desktop/laptop.
Yeah, Tumbleweed has a good track record with NVIDIA drivers in my experience. As with updates in general.
Although I still use X11 as Wayland still has graphical issues in some apps for me. Usually Flatpaks. That makes it unusable for me for the time being.
Edit: I have an older card (1050ti), so maybe I don’t get the latests drivers anymore?? On version 550.